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[Gastroschisis and omphalocele: Incidence and outcome].
Reynisdottir, Kristin Fjola; Hjartardottir, Hulda; Rosmundsson, Thrainn; Thorkelsson, Thordur.
Afiliação
  • Reynisdottir KF; Faculty of medicine, University of Iceland, Child and Adolescent Psychiatric Department, Landspitali - National University Hospital of Iceland.
  • Hjartardottir H; Faculty of medicine, University of Iceland, Obstetrics and Fetal Medicine, Landspitali - National University Hospital of Iceland.
  • Rosmundsson T; Faculty of medicine, University of Iceland, Pediatric Surgery, Landspitali University Hospital.
  • Thorkelsson T; Faculty of medicine, University of Iceland, Neonatal Intensive Care at Children's Hospital, Landspitali - National University Hospital of Iceland.
Laeknabladid ; 110(3): 144-150, 2024.
Article em Is | MEDLINE | ID: mdl-38420959
ABSTRACT

INTRODUCTION:

Gastroschisis and omphalocele are the most common congenital abdominal wall defects. The main purpose of this study was to investigate the incidence, other associated anomalies and the course of these diseases in Iceland. MATERIAL AND

METHODS:

The study was retrospective. The population was all newborns who were admitted to the NICU of Children's Hospital Iceland due to gastroschisis or omphalocele in 1991-2020. Furthermore, all fetuses diagnosed prenatally or post mortem where the pregnancy ended in spontaneous or induced abortion, were included.

RESULTS:

During the study period, 54 infants were born with gastroschisis and five with omphalocele. The incidence of gastroschisis was 4.11 and omphalocele 0,38/10,000 births. There was no significant change in the incidence of the diseases during the study period. In addition, five fetuses were diagnosed with gastroschisis and 31 with omphalocele where the pregnancy was terminated. In addition to gastroschisis in the live born infants and fetuses the most common associated anomalies were in the gastrointestinal or urinary tract but in infants and fetuses with omphalocele anomalies of the cardiac, central nervous or skeletal systems were the most common. Sixteen fetuses diagnosed with omphalocele had trisomy 18. Mothers aged 16-20 were more likely to give birth to an infant with gastroschisis than older mothers (p< 0.001). Primary closure was successful in 86% of the infants. Those reached full feedings significantly earlier and were discharged earlier. Overall survival rate was 95%. Three children were still receiving parenteral nutrition at discharge due to short bowel syndrome.

CONCLUSIONS:

The incidence of gastroschisis in Iceland is in accordance with studies in other countries but but the incidence of omphalocele is lower, which can be partly explained by spontaneous or induced abortions. Other anomalies associated with omphalocele are more severe than those associated with gastroschisis. Primary closure was associated with more benign course. Children with gastroschisis may need prolonged parenteral nutrition due to shortening of their intestines.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Gastrosquise / Hérnia Umbilical Limite: Child / Female / Humans / Infant / Newborn / Pregnancy Idioma: Is Revista: Laeknabladid Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Gastrosquise / Hérnia Umbilical Limite: Child / Female / Humans / Infant / Newborn / Pregnancy Idioma: Is Revista: Laeknabladid Ano de publicação: 2024 Tipo de documento: Article