Successful Treatment of Disseminated Granuloma Annulare with Upadacitinib.
Dermatol Ther (Heidelb)
; 14(3): 813-817, 2024 Mar.
Article
em En
| MEDLINE
| ID: mdl-38438785
ABSTRACT
Disseminated granuloma annulare (DGA) is an inflammatory skin disorder characterized by more than 10 erythematous, raised, ring-shaped plaques. Its treatment remains challenging, with conventional therapies showing variable efficacy. We report the case of a woman in her 50s with a 2-year history of DGA refractory to multiple treatments. Given the recent evidence of the role of the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway in the granuloma annulare pathophysiology, treatment with upadacitinib 30 mg per day was started with rapid effectiveness and good tolerance. This case underscores the potential of JAK inhibitors as promising therapeutic options for recalcitrant granuloma annulare.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Dermatol Ther (Heidelb)
Ano de publicação:
2024
Tipo de documento:
Article