Pleural epithelioid hemangioendothelioma in a 39-Year-old female: a case report.
J Cardiothorac Surg
; 19(1): 118, 2024 Mar 12.
Article
em En
| MEDLINE
| ID: mdl-38475834
ABSTRACT
BACKGROUND:
Epithelioid hemangioendothelioma (EHE) is a rare malignancy of vascular origin which can be primarily be seen in various tissues. EHE originating from the pleura is an even more uncommon subtype which may mimic mesothelioma and pleural carcinomatosis. The prognosis of pleural EHE is poor and there is no consensus on the optimal therapeutic approach. CASE PRESENTATION A 39-year-old middle-eastern female presented with progressive dyspnea and left shoulder discomfort. Chest computed tomography scan revealed a left side pleural effusion and pleural thickening. Pleuroscopy was done and biopsies were taken which were positive for CD31, CD34, CK, factor 8-R-antigen, and vimentin. Patient was diagnosed with pleural epithelioid hemangioendothelioma (PEHE) and chemotherapy was started and underwent extrapleural pneumonectomy 7 months later. Unfortunately, the patient passed away 10 months after diagnosis due to disease complications.CONCLUSIONS:
Once PEHE is suspected in histology it can be confirmed with immunohistochemistry. Chemotherapy, surgery or a combination of both is currently used as the treatment but the standard treatment remains a question.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Derrame Pleural
/
Neoplasias Pleurais
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Hemangioendotelioma Epitelioide
Limite:
Adult
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Female
/
Humans
Idioma:
En
Revista:
J Cardiothorac Surg
Ano de publicação:
2024
Tipo de documento:
Article