The exceptions that prove the rule-a historical view of bedaquiline susceptibility.
Genome Med
; 16(1): 39, 2024 03 13.
Article
em En
| MEDLINE
| ID: mdl-38481348
ABSTRACT
In the accompanying study, Nimmo and colleagues estimated the dates of emergence of mutations in mmpR5 (Rv0678), the most important resistance gene to the anti-tuberculosis drug bedaquiline, in over 3500 geographically diverse Mycobacterium tuberculosis genomes. This provided important insights to improve the design and analysis of clinical trials, as well as the World Health Organization catalogue of resistance mutations, the global reference for interpreting genotypic antimicrobial susceptibility testing results.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
/
3_ND
Base de dados:
MEDLINE
Assunto principal:
Diarilquinolinas
/
Mycobacterium tuberculosis
Limite:
Humans
Idioma:
En
Revista:
Genome Med
Ano de publicação:
2024
Tipo de documento:
Article