Mental Health Conditions in Partners and Adult Children of Stroke Survivors.
JAMA Netw Open
; 7(3): e243286, 2024 Mar 04.
Article
em En
| MEDLINE
| ID: mdl-38483386
ABSTRACT
Importance Family caregiving after critical illness has been associated with several adverse health outcomes, including various aspects of mental health, but research focusing specifically on family members of stroke survivors is limited. Objectives:
To examine the associations of stroke in a partner or parent with the risk of depression, substance use disorders, anxiety disorders, and self-harm or suicide. Design, Setting, andParticipants:
This nationwide, population-based cohort study used data from Danish nationwide administrative and clinical registries (2004-2021). Participants included partners and adult children of survivors of stroke. Data analysis was performed from March to December 2023. Exposure Having a partner or parent who survived stroke. Main Outcomes andMeasures:
The Aalen-Johansen estimator was used to compute propensity score-weighted 3-year absolute risks, risk differences, and risk ratios for depression, substance use disorders, anxiety disorders, and self-harm or suicide among partners or children of survivors of stroke compared with partners or children of survivors of myocardial infarction (MI) and matched individuals from the general population.Results:
The study included a total of 1â¯923â¯732 individuals 70â¯917 partners of stroke survivors (median [IQR] age, 68 [59-76] years; 46â¯369 women [65%]), 70â¯664 partners of MI survivors (median [IQR] age, 65 [55-73] years; 51â¯849 women [73%]), 354â¯570 partners of individuals from the general population (median [IQR] age, 68 [59-76] years; 231â¯833 women [65%]), 207â¯386 adult children of stroke survivors (median [IQR] age, 45 [36-52] years; 99â¯382 women [48%]), 183â¯309 adult children of MI survivors (median [IQR] age, 42 [33-49] years; 88â¯078 women [48%]), and 1â¯036â¯886 adult children of individuals from the general population (median [IQR] age, 45 [36-52] years; 496â¯875 women [48%]). Baseline characteristics were well balanced across cohorts after propensity score weighting. Among partners of stroke survivors, the 3-year absolute risk was 1.0% for depression, 0.7% for substance use disorders, 0.3% for anxiety disorders, and 0.04% for self-harm or suicide. Risk ratio point estimates for the assessed outcomes ranged from 1.14 to 1.42 compared with the general population and from 1.04 to 1.09 compared with partners of MI survivors. The elevated risk of depression in partners of stroke survivors was more pronounced after severe or moderate stroke than after mild stroke. Among adult children of stroke survivors, the 3-year absolute risk was 0.6% for depression, 0.6% for substance use disorders, 0.2% for anxiety disorders, and 0.05% for self-harm or suicide. Both absolute risks and risk ratios for adult children of stroke survivors were smaller than those reported in the partner analyses. Conclusions and Relevance In this cohort study of partners and adult children of stroke survivors, risks of several mental health conditions and self-harm or suicide were moderately higher compared with the general population and, to a lesser extent, partners and adult children of MI survivors. These findings highlight the potential consequences of stroke among family members, particularly partners, and its findings may possibly serve as a quantitative foundation for the development of future stroke rehabilitation services.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Transtornos Relacionados ao Uso de Substâncias
/
Acidente Vascular Cerebral
/
Infarto do Miocárdio
Limite:
Adult
/
Aged
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Female
/
Humans
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Middle aged
Idioma:
En
Revista:
JAMA Netw Open
Ano de publicação:
2024
Tipo de documento:
Article