Unlocking the mystery of the feeder organelle and versatile energy metabolism in Cryptosporidium parvum.

Wang, Dongqiang; Zhu, Guan

Wang, Dongqiang; Zhu, Guan.

Afiliação

Wang D; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, China.
Zhu G; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, China; Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, USA. Electronic address: cryptosporida@gmail.com.

Trends Parasitol ; 40(4): 280-282, 2024 Apr.

Article em En | MEDLINE | ID: mdl-38485578

ABSTRACT

ABSTRACT

Xu and colleagues recently revealed the critical role of Cryptosporidium's feeder organelle in nutrient uptake, showcasing the parasite's ability to harness glucose and glucose-6-phosphate from host cells. This illuminates the sophisticated energy metabolism and survival strategies of the parasite, highlighting potential therapeutic targets.

Assuntos

Criptosporidiose; Cryptosporidium parvum; Cryptosporidium; Humanos; Criptosporidiose/parasitologia; Organelas/metabolismo; Metabolismo Energético

Palavras-chave

Cryptosporidium parvum; aldolase; feeder organelle; glucose transporters; glycogen phosphorylase; hexokinase

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Cryptosporidium parvum / Criptosporidiose / Cryptosporidium Limite: Humans Idioma: En Revista: Trends Parasitol Ano de publicação: 2024 Tipo de documento: Article

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