Occult SMARCA4-Deficient Undifferentiated Carcinoma Unmasked by 68 Ga-FAPI-46 PET/CT.
Clin Nucl Med
; 49(8): 787-789, 2024 Aug 01.
Article
em En
| MEDLINE
| ID: mdl-38537213
ABSTRACT
ABSTRACT SMARCA4-deficient undifferentiated tumors (SMARCA4-dUT) are rare and aggressive neoplasms commonly found in male smokers and portend a poor prognosis. In this case, we reported 18 F-FDG and 68 Ga-FAPI-46 PET/CT findings in an occult SMARCA4-dUT located in the left pulmonary hilum along with mediastinal lymph node metastases. 68 Ga-FAPI-46 PET/CT showed superiority over 18 F-FDG for detecting SMARCA4-dUT lesions. This case highlighted that 68 Ga-FAPI-46 PET/CT may be a promising imaging modality in the evaluation of SMARCA4-dUT, particularly for detecting the occult SMARCA4-dUT arising in uncommon sites.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fatores de Transcrição
/
Proteínas Nucleares
/
Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada
Limite:
Humans
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Male
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Middle aged
Idioma:
En
Revista:
Clin Nucl Med
Ano de publicação:
2024
Tipo de documento:
Article