Endoscopic duodenal mucosa ablation: the future of diabetes treatment?

Musso, Giovanni; Cassader, Maurizio; Gambino, Roberto

Musso, Giovanni; Cassader, Maurizio; Gambino, Roberto.

Afiliação

Musso G; MECAU, San Luigi Gonzaga Hospital, University of Turin, Turin, Italy. Electronic address: gi.musso@sanluigigonzaga.it.
Cassader M; Department of Medical Sciences, Città della Salute e della Scienza, University of Turin, Turin, Italy.
Gambino R; Department of Medical Sciences, Città della Salute e della Scienza, University of Turin, Turin, Italy.

Trends Mol Med ; 30(7): 612-616, 2024 Jul.

Article em En | MEDLINE | ID: mdl-38553333

ABSTRACT

ABSTRACT

Duodenal mucosa ablation (DMA) is a novel approach to treat diabetes, consisting of endoscopic ablation of dysfunctional diabetic duodenal mucosa, which, following the healing response, is replaced by normally functioning mucosa. Two techniques, duodenal mucosal resurfacing (DMR) and recellularization via electroporation therapy (ReCET), recently showed promise in type 2 diabetes mellitus (T2DM) patients.

Assuntos

Diabetes Mellitus Tipo 2; Duodeno; Mucosa Intestinal; Animais; Humanos; Diabetes Mellitus Tipo 2/cirurgia; Diabetes Mellitus Tipo 2/terapia; Duodeno/cirurgia; Mucosa Intestinal/cirurgia

Palavras-chave

ReCET; duodenal mucosal resurfacing; electroporation therapy; recellularization

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Duodeno / Mucosa Intestinal Limite: Animals / Humans Idioma: En Revista: Trends Mol Med Ano de publicação: 2024 Tipo de documento: Article

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