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Appendicular Muscle Mass Index as the Most Important Determinant of Bone Mineral Content and Density in Small for Gestational Age Children.
Rojo-Trejo, María Elena; Robles-Osorio, Ma Ludivina; Rangel, Beatriz; García, Olga P; Becerra-Hernández, María Fernanda; Cárdenas-Rodríguez, Laura; Sabath, Ernesto.
Afiliação
  • Rojo-Trejo ME; Nutrition School, Universidad Autónoma de Querétaro, Querétaro, México.
  • Robles-Osorio ML; Nutrition School, Universidad Autónoma de Querétaro, Querétaro, México.
  • Rangel B; Nutrition School, Universidad Autónoma de Querétaro, Querétaro, México.
  • García OP; Nutrition School, Universidad Autónoma de Querétaro, Querétaro, México.
  • Becerra-Hernández MF; Renal Division and Metabolic Unit, Hospital General de Querétaro, Queretaro, México.
  • Cárdenas-Rodríguez L; Renal Division and Metabolic Unit, Hospital General de Querétaro, Queretaro, México.
  • Sabath E; Nutrition School, Universidad Autónoma de Querétaro, Querétaro, México.
Clin Pediatr (Phila) ; : 99228241242515, 2024 Apr 06.
Article em En | MEDLINE | ID: mdl-38581300
ABSTRACT
Preterm small for gestational age (SGA) children are at increased risk for low bone mineral content later in life; however, data on SGA children born at term are scarce. We included 44 SGA and 57 adequate for gestational age (AGA) children aged 6 to 11 years to compare bone mineral density (BMD) and bone mineral content (BMC) and to identify which anthropometric and biochemical values influence bone mineralization in these children. Fat mass, appendicular skeletal muscle mass index (ASMMI), BMC, and BMD were significantly lower in SGA children than in AGA (P ≤ .005). Appendicular muscle mass index correlated with BMC(TBLH,FN,L1-L4) and BMD(TBLH,FN,L1-L4) in both groups (r2 = 0.7, P < .05). In multivariate analysis, ASMMI was strongly associated with BMC and BMD in both groups. There were no differences in clinical biomarkers, calcium intake, and physical activity between the groups. Achieving adequate muscle mass contributes to adequate bone mineralization and a lower risk for low BMC and BMD in SGA children.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Clin Pediatr (Phila) Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Clin Pediatr (Phila) Ano de publicação: 2024 Tipo de documento: Article