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Allogeneic CD19/CD22 CAR T-Cell Therapy for B-Cell Acute Lymphoblastic Leukemia.
Phely, Laurent; Hensen, Luca; Faul, Christoph; Ruff, Christer Alexander; Schneider, Dina; Bethge, Wolfgang Andreas; Lengerke, Claudia.
Afiliação
  • Phely L; Department of Internal Medicine II, Hematology, Oncology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, Tuebingen, Germany.
  • Hensen L; Department of Internal Medicine II, Hematology, Oncology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, Tuebingen, Germany.
  • Faul C; Department of Internal Medicine II, Hematology, Oncology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, Tuebingen, Germany.
  • Ruff CA; Department of Diagnostic and Interventional Neuroradiology, University Hospital Tubingen, Tubingen, Germany.
  • Schneider D; Miltenyi Biotec, Gaithersburg, Maryland.
  • Bethge WA; Department of Internal Medicine II, Hematology, Oncology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, Tuebingen, Germany.
  • Lengerke C; Department of Internal Medicine II, Hematology, Oncology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, Tuebingen, Germany.
JAMA Oncol ; 10(6): 821-824, 2024 Jun 01.
Article em En | MEDLINE | ID: mdl-38635232
This case series reports durable remissions in 2 patients with relapsed/refractory B-cell acute lymphoblastic leukemia treated with allogeneic bispecific CD19/CD22-targeting chimeric antigen receptor T cells.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras B / Imunoterapia Adotiva / Antígenos CD19 / Lectina 2 Semelhante a Ig de Ligação ao Ácido Siálico Limite: Adult / Female / Humans / Male Idioma: En Revista: JAMA Oncol Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras B / Imunoterapia Adotiva / Antígenos CD19 / Lectina 2 Semelhante a Ig de Ligação ao Ácido Siálico Limite: Adult / Female / Humans / Male Idioma: En Revista: JAMA Oncol Ano de publicação: 2024 Tipo de documento: Article