Muscle stem cell niche dynamics during muscle homeostasis and regeneration.
Curr Top Dev Biol
; 158: 151-177, 2024.
Article
em En
| MEDLINE
| ID: mdl-38670704
ABSTRACT
The process of skeletal muscle regeneration involves a coordinated interplay of specific cellular and molecular interactions within the injury site. This review provides an overview of the cellular and molecular components in regenerating skeletal muscle, focusing on how these cells or molecules in the niche regulate muscle stem cell functions. Dysfunctions of muscle stem cell-to-niche cell communications during aging and disease will also be discussed. A better understanding of how niche cells coordinate with muscle stem cells for muscle repair will greatly aid the development of therapeutic strategies for treating muscle-related disorders.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Regeneração
/
Músculo Esquelético
/
Nicho de Células-Tronco
/
Homeostase
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Curr Top Dev Biol
Ano de publicação:
2024
Tipo de documento:
Article