Exploring the role of OXTR gene methylation in attachment development: A longitudinal study.
Dev Psychobiol
; 66(5): e22496, 2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-38689124
ABSTRACT
The current study explored longitudinally whether oxytocin receptor gene methylation (OXTRm) changes moderated the association between parental sensitivity changes and children's attachment changes over three waves. Six hundred six Flemish children (10-12 years, 42.8%-44.8% boys) completed attachment measures and provided salivary OXTRm data on seven CpG sites. Their parents reported their sensitive parenting. Results suggest that OXTRm changes hardly link to attachment (in)security changes after the age of 10. Some support was found for interaction effects between parental sensitivity changes and OXTRm changes on attachment changes over time. Effects suggest that for children with increased OXTRm in the promotor region and decreased methylation in the inhibitor region over time, increased parental sensitivity was associated with increased secure attachment and decreased insecure attachment over time.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Receptores de Ocitocina
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Metilação de DNA
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Apego ao Objeto
Limite:
Child
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Female
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Humans
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Male
Idioma:
En
Revista:
Dev Psychobiol
Ano de publicação:
2024
Tipo de documento:
Article