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Inter-fractional error and intra-fractional motion of prostate and dosimetry comparisons of patient position registrations with versus without fiducial markers during treatment with carbon-ion radiotherapy.
Iwai, Yuma; Mori, Shinichiro; Ishikawa, Hitoshi; Kanematsu, Nobuyuki; Matsumoto, Shinnosuke; Nakaji, Taku; Okonogi, Noriyuki; Kobayashi, Kana; Wakatsuki, Masaru; Uno, Takashi; Yamada, Shigeru.
Afiliação
  • Iwai Y; National Institutes for Quantum Science and Technology, QST Hospital, Chiba, Japan.
  • Mori S; Department of Accelerator and Medical Physics, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba, 263-8555, Japan. mori.shinichiro@qst.go.jp.
  • Ishikawa H; National Institutes for Quantum Science and Technology, QST Hospital, Chiba, Japan.
  • Kanematsu N; Department of Accelerator and Medical Physics, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba, 263-8555, Japan.
  • Matsumoto S; Department of Accelerator and Medical Physics, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba, 263-8555, Japan.
  • Nakaji T; Department of Accelerator and Medical Physics, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba, 263-8555, Japan.
  • Okonogi N; National Institutes for Quantum Science and Technology, QST Hospital, Chiba, Japan.
  • Kobayashi K; National Institutes for Quantum Science and Technology, QST Hospital, Chiba, Japan.
  • Wakatsuki M; National Institutes for Quantum Science and Technology, QST Hospital, Chiba, Japan.
  • Uno T; Department of Radiology, Chiba University Hospital, Chiba, Japan.
  • Yamada S; National Institutes for Quantum Science and Technology, QST Hospital, Chiba, Japan.
Radiol Phys Technol ; 17(2): 504-517, 2024 Jun.
Article em En | MEDLINE | ID: mdl-38691309
ABSTRACT
A few reports have discussed the influence of inter-fractional position error and intra-fractional motion on dose distribution, particularly regarding a spread-out Bragg peak. We investigated inter-fractional and intra-fractional prostate position error by monitoring fiducial marker positions. In 2020, data from 15 patients with prostate cancer who received carbon-ion beam radiotherapy (CIRT) with gold markers were investigated. We checked marker positions before and during irradiation to calculate the inter-fractional positioning and intra-fractional movement and evaluated the CIRT dose distribution by adjusting the planning beam isocenter and clinical target volume (CTV) position. We compared the CTV dose coverages (CTV receiving 95% [V95%] or 98% [V98%] of the prescribed dose) between skeletal and fiducial matching irradiation on the treatment planning system. For inter-fractional error, the mean distance between the marker position in the planning images and that in a patient starting irradiation with skeletal matching was 1.49 ± 1.11 mm (95th percentile = 1.85 mm). The 95th percentile (maximum) values of the intra-fractional movement were 0.79 mm (2.31 mm), 1.17 mm (2.48 mm), 1.88 mm (4.01 mm), 1.23 mm (3.00 mm), and 2.09 mm (8.46 mm) along the lateral, inferior, superior, dorsal, and ventral axes, respectively. The mean V95% and V98% were 98.2% and 96.2% for the skeletal matching plan and 99.5% and 96.8% for the fiducial matching plan, respectively. Fiducial matching irradiation improved the CTV dose coverage compared with skeletal matching irradiation for CIRT for prostate cancer.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Planejamento da Radioterapia Assistida por Computador / Posicionamento do Paciente / Marcadores Fiduciais / Radioterapia com Íons Pesados / Movimento Limite: Aged / Humans / Male Idioma: En Revista: Radiol Phys Technol Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Planejamento da Radioterapia Assistida por Computador / Posicionamento do Paciente / Marcadores Fiduciais / Radioterapia com Íons Pesados / Movimento Limite: Aged / Humans / Male Idioma: En Revista: Radiol Phys Technol Ano de publicação: 2024 Tipo de documento: Article