Association between the triglyceride-glucose index and subclinical left ventricular systolic dysfunction in obese patients.
Cardiovasc Diabetol
; 23(1): 161, 2024 May 07.
Article
em En
| MEDLINE
| ID: mdl-38715070
ABSTRACT
BACKGROUND:
The association between the triglyceride-glucose (TyG) index and subclinical left ventricular (LV) systolic dysfunction in obese patients remains unclear. This study aimed to investigate the relationship between the TyG index and LV global longitudinal strain (GLS) in obese patients.METHODS:
A total of 1028 obese patients from January 2019 to January 2024 were included in the present study. Clinical parameters and biochemical and echocardiographic data were obtained from the participants. LV GLS was obtained from the GE EchoPAC workstation for evaluating subclinical LV function. The TyG index was calculated as Ln (fasting TG [mg/dL] × fasting glucose [mg/dL]/2). LV GLS was compared between obese patients with a high TyG index and those with a low TyG index.RESULTS:
Obese patients with a high TyG index had greater incidences of hypertension, diabetes mellitus and hyperlipidaemia. The LV GLS was significantly lower in the high TyG index group than in the low TyG index group (P = 0.01). After adjusting for sex, age, body mass index, heart rate, hypertension, diabetes mellitus, dyslipidaemia, blood urea nitrogen, serum creatinine, LV mass and LV hypertrophy, the TyG index remained an independent risk indicator related to an LV GLS < 20% (OR 1.520, 95% CI 1.040 to 2.221; P = 0.031).CONCLUSIONS:
We concluded that an increase in the TyG index is independently associated with subclinical LV systolic dysfunction in obese patients.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Triglicerídeos
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Glicemia
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Biomarcadores
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Função Ventricular Esquerda
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Disfunção Ventricular Esquerda
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Doenças Assintomáticas
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Obesidade
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Cardiovasc Diabetol
Ano de publicação:
2024
Tipo de documento:
Article