Trends in experimental autoimmune prostatitis: insights into pathogenesis, therapeutic strategies, and redefinition.
Am J Clin Exp Urol
; 12(2): 52-63, 2024.
Article
em En
| MEDLINE
| ID: mdl-38736617
ABSTRACT
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPSS) is a debilitating condition characterized by prostate inflammation, pain and urinary symptoms. The immune system's response to self-antigens is a contributing factor to CP/CPSS. In this review, we examine the use of experimental autoimmune prostatitis (EAP) in rodents to model salient features of autoimmune mediated CP/CPSS. By exploring etiological factors, immunological mechanisms, and emerging therapeutic strategies, our aim is to enhance our understanding of CP/CPSS pathogenesis and promote the development of strategies to test innovative interventions using the EAP pre-clinical model.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Am J Clin Exp Urol
Ano de publicação:
2024
Tipo de documento:
Article