Treatment of primary cardiac diffuse large B-cell lymphoma involving the coronary sinus with R-EPOCH: a case report and literature review.
Ann Hematol
; 103(7): 2557-2560, 2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-38748259
ABSTRACT
Primary cardiac lymphomas (PCLs) are a rare clinical entity, in which treatment guidelines remain to be established. Rituximab, etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin (R-EPOCH) has been proposed, given that it involves a continuous infusion of anthracycline, reducing the risk of a cardiotoxicity and therefore the theoretical risk of perforation. However, the literature on this method of treatment is scarce. Herein, we present a unique case of a 75-year-old male, diagnosed with primary cardiac diffuse large B-cell lymphoma (DLBCL) with relatively unusual involvement of the coronary sinus, treated first with one cycle of R-EPOCH, followed by three cycles of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) to reduce said risk. To our knowledge, this is one of two cases, in which a patient with PCL was treated this way.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vincristina
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Prednisona
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Protocolos de Quimioterapia Combinada Antineoplásica
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Doxorrubicina
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Linfoma Difuso de Grandes Células B
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Ciclofosfamida
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Etoposídeo
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Seio Coronário
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Rituximab
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Neoplasias Cardíacas
Limite:
Aged
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Humans
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Male
Idioma:
En
Revista:
Ann Hematol
Ano de publicação:
2024
Tipo de documento:
Article