Association of temperature and absolute humidity with incidence of exercise-induced bronchoconstriction in children.
Acta Paediatr
; 113(8): 1942-1948, 2024 Aug.
Article
em En
| MEDLINE
| ID: mdl-38780114
ABSTRACT
AIM:
Exercise test outdoors is widely used to diagnose asthma in children, but it is unclear how much outdoor air factors affect the results.METHODS:
We analysed 321 outdoor exercise challenge tests with spirometry in children 6-16 years conducted due to suspicion of asthma or for assessing the effect of medication on asthma. We studied the association of FEV1 decrease and incidence of exercise-induced bronchoconstriction (EIB) with temperature, relative humidity (RH) and absolute humidity (AH).RESULTS:
Asthma was diagnosed in 57% of the subjects. AH ≥5 g/m3, but not RH or temperature, was associated with the EIB incidence (p = 0.035). In multivariable logistic regression, AH ≥5 g/m3 was negatively associated (OR = 0.51, 95% CI [0.28â0.92], p = 0.026) while obstruction before exercise (OR = 2.11, 95% CI [1.16â3.86], p = 0.015) and IgE-mediated sensitisation were positively associated with EIB (OR = 2.24, 95% CI [1.11â4.51], p = 0.025). AH (r = -0.12, p = 0.028) and temperature (r = -0.13, p = 0.023) correlated with decrease in FEV1. In multivariable linear regression, only AH was associated with FEV1 decrease (coefficient = -0.044, 95% CI [-0.085 to -0.004], p = 0.033).CONCLUSION:
AH of outdoor air associates with occurrence and severity of EIB in outdoor exercise tests in children. Care should be taken when interpreting negative outdoor exercise test results if AH of air is high.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Asma Induzida por Exercício
/
Temperatura
/
Umidade
Limite:
Adolescent
/
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Acta Paediatr
Ano de publicação:
2024
Tipo de documento:
Article