Malignant melanoma in a 12-year-old boy 17 months after completing hepatoblastoma treatment.
Cancer Rep (Hoboken)
; 7(5): e2118, 2024 May.
Article
em En
| MEDLINE
| ID: mdl-38801212
ABSTRACT
BACKGROUND:
Melanoma is rare as a secondary malignant neoplasm among childhood cancer survivors. CASE We report a case of a 12-year-old boy who developed malignant melanoma with systemic metastases 17 months after completing treatment for hepatoblastoma. The diagnosis was made unexpectedly based on a bone marrow examination. The patient did not respond to immune checkpoint inhibitor therapy and died 6 weeks after being diagnosed with melanoma. Whole-exome sequencing to examine 103 genes associated with cancer predisposition did not identify any germ-line variants.CONCLUSION:
This case study provides a unique example of melanoma in a childhood cancer survivor following hepatoblastoma treatment but does not identify any candidate variant to link hepatoblastoma and melanoma.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hepatoblastoma
/
Neoplasias Hepáticas
/
Melanoma
Limite:
Child
/
Humans
/
Male
Idioma:
En
Revista:
Cancer Rep (Hoboken)
Ano de publicação:
2024
Tipo de documento:
Article