Electrochemical Synthesis of Phosphorylated Indoles and Trp-Containing Oligopeptides.
Org Lett
; 26(22): 4700-4704, 2024 Jun 07.
Article
em En
| MEDLINE
| ID: mdl-38804550
ABSTRACT
Cp2Fe-mediated electrochemical synthesis of phosphorylated indoles and Trp-containing oligopeptides has been developed, which eliminates the need for external oxidants and yields the desired products in moderate to excellent yields under mild conditions. Importantly, the synthetic applicability was further demonstrated through its easy scalability and the anticancer activity of the product. Remarkably, it presents the first electrochemical protocol to access the phosphorylation of indoles and Trp-containing oligopeptides.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oligopeptídeos
/
Indóis
Limite:
Humans
Idioma:
En
Revista:
Org Lett
Ano de publicação:
2024
Tipo de documento:
Article