A Wireless Battery-Free Implant With Optical Telemetry for In Vivo Cortical Stimulation.
IEEE Sens Lett
; 8(5)2024 May.
Article
em En
| MEDLINE
| ID: mdl-38818033
ABSTRACT
We present a 100 µm-thick, wireless, and battery-free implant for brain stimulation through a U.S. Food and Drug Administration-approved collagen dura substitute without contact with the brain's surface, while providing visible-light spectrum telemetry to track the onset of stimulation. The device is fabricated on a 16 × 6.67 mm2 biocompatible parylene/PDMS substrate and is encapsulated with a 2 µm-thick transparent parylene layer that enables the relay of the LED brightness. The in vivo rodent testing confirmed the implant's ability to trigger motor response while generating observable brightness through the skin. The results reveal the prospect of wireless stimulation with enhanced safety by eliminating contact between the implant and the brain, with optical telemetry for facilitated tracking.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
IEEE Sens Lett
Ano de publicação:
2024
Tipo de documento:
Article