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Generation of an iPSC line from a 79-year-old female patient diagnosed with sporadic Parkinson's disease.
Liu, Jingrui; Du, Juan; Ma, Xiaowei; Jin, Yuchuan; Yang, Qian; Zhai, Yingtong; Cheng, Jingke; Luan, Feng; Ma, Min; Zhang, Zhanchi; Ren, Qian; Cui, Huixian.
Afiliação
  • Liu J; International Cooperation Laboratory of Stem Cell Research, Institute of Medical and Health Science, Hebei Medical University, Shijiazhuang 050017, China; Department of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang 050017, China.
  • Du J; Department of Human Anatomy, Hebei Medical University, Shijiazhuang 050017, China; Human Brain Bank, Hebei Medical University, Shijiazhuang, China; Hebei Key Laboratory of Neurodegenerative Disease Mechanism, Hebei Medical University, Shijiazhuang, China.
  • Ma X; Department of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, P.R. China.
  • Jin Y; Department of Human Anatomy, Hebei Medical University, Shijiazhuang 050017, China; Human Brain Bank, Hebei Medical University, Shijiazhuang, China.
  • Yang Q; Department of Human Anatomy, Hebei Medical University, Shijiazhuang 050017, China; Human Brain Bank, Hebei Medical University, Shijiazhuang, China.
  • Zhai Y; Department of Human Anatomy, Hebei Medical University, Shijiazhuang 050017, China; International Cooperation Laboratory of Stem Cell Research, Institute of Medical and Health Science, Hebei Medical University, Shijiazhuang 050017, China.
  • Cheng J; Department of Human Anatomy, Hebei Medical University, Shijiazhuang 050017, China; International Cooperation Laboratory of Stem Cell Research, Institute of Medical and Health Science, Hebei Medical University, Shijiazhuang 050017, China.
  • Luan F; Department of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang 050017, China.
  • Ma M; Department of Human Anatomy, Hebei Medical University, Shijiazhuang 050017, China; Hebei Key Laboratory of Neurodegenerative Disease Mechanism, Hebei Medical University, Shijiazhuang, China.
  • Zhang Z; Department of Human Anatomy, Hebei Medical University, Shijiazhuang 050017, China; Hebei Research Center for Stem Cell Medical Translational Engineering, Shijiazhuang 050017, China; Hebei Key Laboratory of Neurodegenerative Disease Mechanism, Hebei Medical University, Shijiazhuang, China.
  • Ren Q; Department of Human Anatomy, Hebei Medical University, Shijiazhuang 050017, China; International Cooperation Laboratory of Stem Cell Research, Institute of Medical and Health Science, Hebei Medical University, Shijiazhuang 050017, China; Hebei Research Center for Stem Cell Medical Translational Engi
  • Cui H; Department of Human Anatomy, Hebei Medical University, Shijiazhuang 050017, China; International Cooperation Laboratory of Stem Cell Research, Institute of Medical and Health Science, Hebei Medical University, Shijiazhuang 050017, China; Hebei Research Center for Stem Cell Medical Translational Engi
Stem Cell Res ; 78: 103450, 2024 Aug.
Article em En | MEDLINE | ID: mdl-38820865
ABSTRACT
Parkinson's disease is a common neurodegenerative disorder. Here we present a human induced pluripotent stem cells (iPSCs) derived from peripheral blood mononuclear cells (PBMCs) of a 79-year-old female patient diagnosed with sporadic Parkinson's disease using the sendai virus. Generated iPSCs maintain normal karyotype, exhibit pluripotent stem cell markers, and possess differentiation potential. The iPSCs allows for differentiation into various cell subtypes, providing conditions for the research of the pathogenesis and drug development of Parkinson's disease.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Diferenciação Celular / Células-Tronco Pluripotentes Induzidas Limite: Aged / Female / Humans Idioma: En Revista: Stem Cell Res Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Diferenciação Celular / Células-Tronco Pluripotentes Induzidas Limite: Aged / Female / Humans Idioma: En Revista: Stem Cell Res Ano de publicação: 2024 Tipo de documento: Article