Multi-cell-line learning for the data-driven construction of mechanistic metabolic models.

Lu, Yen-An; McCann, Meghan G; Hu, Wei-Shou; Zhang, Qi

Lu, Yen-An; McCann, Meghan G; Hu, Wei-Shou; Zhang, Qi.

Afiliação

Lu YA; Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, Minnesota, USA.
McCann MG; Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, Minnesota, USA.
Hu WS; Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, Minnesota, USA.
Zhang Q; Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, Minnesota, USA.

Biotechnol Bioeng ; 121(9): 2833-2847, 2024 Sep.

Article em En | MEDLINE | ID: mdl-38831695

Assuntos

Cricetulus; Modelos Biológicos; Células CHO; Animais; Aprendizado de Máquina; Transcriptoma/genética

Palavras-chave

Chinese hamster ovary cell; mechanistic metabolic model; multitask learning; parameter estimation; transcriptome

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cricetulus / Modelos Biológicos Limite: Animals Idioma: En Revista: Biotechnol Bioeng Ano de publicação: 2024 Tipo de documento: Article

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