Impact of the COVID-19 pandemic on the utilisation and quality of antibiotic use in the Scottish primary care setting: a population-based segmented interrupted time-series analysis.
Expert Rev Anti Infect Ther
; : 1-11, 2024 Jun 14.
Article
em En
| MEDLINE
| ID: mdl-38836493
ABSTRACT
BACKGROUND:
Inappropriate use of antibiotics is expected to increase during the COVID-19 pandemic, but there are limited data on COVID-19's long-term impact. We assessed the impact of COVID-19 on the quantity and quality of antibiotic use in Scotland. RESEARCH DESIGN ANDMETHODS:
A segmented interrupted time series was applied to monthly dispensed antibiotics using prescription cost analysis data from March/2019 to March/2023. Antibiotic use was quantified using the number of items dispensed/1000 inhabitants (TIDs) and defined daily dose/1000 inhabitants/day (DIDs). The quality of antibiotic use was assessed using key quality indicators including the WHO AWaRe classification, proportion of broad-spectrum and "4C"-antibiotics.RESULTS:
Overall, for all antibiotics, there was a non-significant increase in TIDs and DIDs before the first lockdown (March/2020) (ß1), but a decline in the level immediately after the first (ß2) and second lockdowns (ß4) (November/2020), albeit non-significant. However, a significant increase in the time trend after the second lockdown (ß5) for all antibiotic classes was observed. COVID-19 had no negative impact on AWaRe utilisation, with the proportion of all antibiotics from the Access group increasing from 76% in March/2019 to 90% in March/2023. The proportion of "4C" antibiotic reduced significantly after the second lockdown.CONCLUSIONS:
Neither the utilisation nor the quality of total antibiotic use appeared to have been significantly affected by COVID-19.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Expert Rev Anti Infect Ther
Ano de publicação:
2024
Tipo de documento:
Article