Downstaging strategies for unresectable hepatocellular carcinoma.
World J Gastroenterol
; 30(20): 2731-2733, 2024 May 28.
Article
em En
| MEDLINE
| ID: mdl-38855157
ABSTRACT
A significant number of patients with hepatocellular carcinoma (HCC) are usually diagnosed in advanced stages, that leads to inability to achieve cure. Palliative options are focusing on downstaging a locally advanced disease. It is well-supported in the literature that patients with HCC who undergo successful conversion therapy followed by curative-intent surgery may achieve a significant survival benefit compared to those who receive chemotherapy alone or those who are successfully downstaged with conversion therapy but not treated with surgery. Hepatic artery infusion chemotherapy can be a potential downstaging strategy, since recent studies have demonstrated excellent outcomes in patients with colorectal liver metastatic disease as well as primary liver malignancies.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infusões Intra-Arteriais
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Carcinoma Hepatocelular
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Neoplasias Hepáticas
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Estadiamento de Neoplasias
Limite:
Humans
Idioma:
En
Revista:
World J Gastroenterol
Ano de publicação:
2024
Tipo de documento:
Article