A Pt nanoenzyme- and BODIPY-loaded nanoscale covalent organic framework for relieving intratumoural hypoxia to enhance photodynamic therapy.
Dalton Trans
; 53(27): 11242-11246, 2024 Jul 09.
Article
em En
| MEDLINE
| ID: mdl-38919991
ABSTRACT
Herein, we report a composite COF material loaded with a Pt nanoenzyme and an organic photosensitizer BODIPY, synthesized via a stepwise post-synthetic modification. The obtained Pt@COF-BDP nanoparticles can efficiently and continuously convert H2O2 to O2, thereby increasing the efficiency of single-linear oxygen production and achieving efficient tumor inhibition.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fotoquimioterapia
/
Platina
/
Compostos de Boro
/
Fármacos Fotossensibilizantes
/
Estruturas Metalorgânicas
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Dalton Trans
Ano de publicação:
2024
Tipo de documento:
Article