Clinical utility of PET/MRI in multiple myeloma.
Ann Acad Med Singap
; 52(11): 590-600, 2023 Nov 29.
Article
em En
| MEDLINE
| ID: mdl-38920148
ABSTRACT
Introduction:
This study aimed to evaluate the clinical utility of positron emission tomography/magnetic resonance imaging (PET/MRI), especially in comparison with PET/computed tomography (CT), which has been widely used in clinical practice in multiple myeloma.Method:
F-18 fluorodeoxyglucose PET/MRI and PET/ CT studies were done at baseline and when at least a partial response to treatment was achieved. These were done for newly-diagnosed myeloma patients who have not had more than 1 cycle of anti-myeloma treatment, or for relapsed and/or refractory myeloma patients before the start of next line of therapy.Results:
PET/MRI correlated significantly with PET/CT, in terms of number of lesions detected, standardised uptake value (SUVmean and SUVmax, both at baseline and post-treatment. PET/MRI and PET/CT correlated with survival at baseline, but not post-treatment.Conclusion:
In this study, PET/MRI was more sensitive in detecting early disease and disease resolution post-treatment, compared with PET/CT. However, PET/MRI was less sensitive in detecting lesions in the ribs, clavicle and skull.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Imageamento por Ressonância Magnética
/
Fluordesoxiglucose F18
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Tomografia por Emissão de Pósitrons
/
Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada
/
Mieloma Múltiplo
Limite:
Adult
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Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Ann Acad Med Singap
Ano de publicação:
2023
Tipo de documento:
Article