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Advancements in Antiviral Drug Development: Comprehensive Insights into Design Strategies and Mechanisms Targeting Key Viral Proteins.
Hangyu, Wang; Panpan, Li; Jie, Shen; Hongyan, Wang; Linmiao, Wei; Kangning, Han; Yichen, Shi; Shuai, Wang; Cheng, Wang.
Afiliação
  • Hangyu W; Key Laboratory of Immune Microenvironment and Inflammatory Disease Research in Universities of Shandong Province, School of Basic Medical Sciences, Shandong Second Medical University, Weifang 261053, P.R. China.
  • Panpan L; Key Laboratory of Immune Microenvironment and Inflammatory Disease Research in Universities of Shandong Province, School of Basic Medical Sciences, Shandong Second Medical University, Weifang 261053, P.R. China.
  • Jie S; School of Medical Laboratory, Shandong Second Medical University, Weifang 261053, P.R. China.
  • Hongyan W; Key Laboratory of Immune Microenvironment and Inflammatory Disease Research in Universities of Shandong Province, School of Basic Medical Sciences, Shandong Second Medical University, Weifang 261053, P.R. China.
  • Linmiao W; Key Laboratory of Immune Microenvironment and Inflammatory Disease Research in Universities of Shandong Province, School of Basic Medical Sciences, Shandong Second Medical University, Weifang 261053, P.R. China.
  • Kangning H; Key Laboratory of Immune Microenvironment and Inflammatory Disease Research in Universities of Shandong Province, School of Basic Medical Sciences, Shandong Second Medical University, Weifang 261053, P.R. China.
  • Yichen S; School of Stomatology, Shandong Second Medical University, Weifang 261053, P.R. China.
  • Shuai W; Department of Rheumatology and Immunology, The Affiliated Hospital of Inner Mongolia Medical University, Inner Mongolia 010050, P.R. China.
  • Cheng W; Inner Mongolia Key Laboratory for Pathogenesis and Diagnosis of Rheumatic and Autoimmune Diseases, Inner Mongolia 010110, P.R. China.
J Microbiol Biotechnol ; 34(7): 1376-1384, 2024 Jul 28.
Article em En | MEDLINE | ID: mdl-38934770
ABSTRACT
Viral infectious diseases have always been a threat to human survival and quality of life, impeding the stability and progress of human society. As such, researchers have persistently focused on developing highly efficient, low-toxicity antiviral drugs, whether for acute or chronic infectious diseases. This article presents a comprehensive review of the design concepts behind virus-targeted drugs, examined through the lens of antiviral drug mechanisms. The intention is to provide a reference for the development of new, virus-targeted antiviral drugs and guide their clinical usage.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Proteínas Virais / Viroses / Desenvolvimento de Medicamentos Limite: Humans Idioma: En Revista: J Microbiol Biotechnol Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Proteínas Virais / Viroses / Desenvolvimento de Medicamentos Limite: Humans Idioma: En Revista: J Microbiol Biotechnol Ano de publicação: 2024 Tipo de documento: Article