Next-Generation Vaccine Development with Nanomaterials: Recent Advances, Possibilities, and Challenges.
Annu Rev Biomed Eng
; 26(1): 273-306, 2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-38959389
ABSTRACT
Nanomaterials are becoming important tools for vaccine development owing to their tunable and adaptable nature. Unique properties of nanomaterials afford opportunities to modulate trafficking through various tissues, complement or augment adjuvant activities, and specify antigen valency and display. This versatility has enabled recent work designing nanomaterial vaccines for a broad range of diseases, including cancer, inflammatory diseases, and various infectious diseases. Recent successes of nanoparticle vaccines during the coronavirus disease 2019 (COVID-19) pandemic have fueled enthusiasm further. In this review, the most recent developments in nanovaccines for infectious disease, cancer, inflammatory diseases, allergic diseases, and nanoadjuvants are summarized. Additionally, challenges and opportunities for clinical translation of this unique class of materials are discussed.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Nanoestruturas
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SARS-CoV-2
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COVID-19
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Desenvolvimento de Vacinas
Limite:
Animals
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Humans
Idioma:
En
Revista:
Annu Rev Biomed Eng
Ano de publicação:
2024
Tipo de documento:
Article