Cancer incidence in a cohort of Danish firefighters: An extended long-term follow-up 1968-2021.
Am J Ind Med
; 67(9): 857-864, 2024 Sep.
Article
em En
| MEDLINE
| ID: mdl-38965801
ABSTRACT
OBJECTIVES:
To update and extend the examination of cancer incidence in a cohort of Danish firefighters, now adding 7 years of follow-up and 2766 additional firefighters. The primary focus was directed toward cancer sites that recently contributed to the hazard evaluation conducted by the International Agency for Research on Cancer (IARC).METHODS:
The updated cohort consisted of 11,827 male Danish firefighters who were followed up for cancer from 1968 to 2021. Cohort cancer morbidity was compared with a working population reference group, and standardized incidence ratios (SIR) were used for estimation of relative risks, along with 95% confidence intervals (95% CI).RESULTS:
Among full-time firefighters, SIR of skin melanoma was 1.30 (95% CI 1.02-1.66), and SIR = 1.37 (95% CI 1.02-1.85) for over 5 years of employment. Slightly positive associations were also observed for cancer of the urinary bladder (SIR = 1.16; 95% CI 0.93-1.45), prostate (SIR = 1.11; 95% CI 0.97-1.28), and testis (SIR = 1.11; 95% CI 0.75-1.63).CONCLUSIONS:
This updated study provides evidence indicating an elevated risk of skin melanoma in firefighters. Consistent with IARC's evaluation, we also identified positive associations for urinary bladder, prostate, and testis cancer. In contrast, our findings did not suggest an increased risk of colon cancer, non-Hodgkin lymphoma, and mesothelioma. The latter may be due to small numbers in our still relatively young cohort. Continuous follow-up for cancer in firefighters is warranted, including assessment of influence from surveillance bias.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
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Bombeiros
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Melanoma
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Neoplasias
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Doenças Profissionais
Limite:
Adult
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Aged
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Humans
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Male
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Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
Am J Ind Med
Ano de publicação:
2024
Tipo de documento:
Article