Basic implications on three pathways associated with SARS-CoV-2.

ABSTRACT

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts between the host and virus and govern induction, resulting in multiorgan impacts. Its pathophysiology involves the followings 1) the angiotensin-converting enzyme (ACE2) and Toll-like receptor (TLR) pathways 2) the neuropilin (NRP) pathway 3) the spike protein pathway. Therefore, it is necessary to block the pathological course with modulating innate lymphoid cells against diverse corona variants in the future.