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Case Report of Minimal Change Disease in the Adult Population.
Wynn, Austin B; Metuku, Rajesh; Santos, Raul.
Afiliação
  • Wynn AB; Osteopathic Medicine, Alabama College of Osteopathic Medicine, Dothan, USA.
  • Metuku R; Osteopathic Medicine, Alabama College of Osteopathic Medicine, Dothan, USA.
  • Santos R; Nephrology, Archbold Memorial Hospital, Thomasville, USA.
Cureus ; 16(6): e62306, 2024 Jun.
Article em En | MEDLINE | ID: mdl-39006643
ABSTRACT
Minimal change disease (MCD), typically linked with pediatric nephrotic syndrome, presents challenges in early identification and diagnosis in adult populations. This case report emphasizes the importance of tailored diagnostic and treatment approaches for adults with MCD. Our patient presented with fatigue, shortness of breath, and confusion, along with other symptoms leading to a renal biopsy which confirmed MCD. This highlights the diagnostic significance of kidney biopsy in adults. While steroids remain the standard treatment, challenges such as resistance and side effects lead to the consideration of alternatives like tacrolimus. There are nuanced differences between adult and pediatric MCD presentations, for which our study calls for increased awareness among physicians. Steroids are considered a first-line treatment for MCD, but prolonged use of steroids has significantly increased risk and alternative therapies should be considered. This study presents an example of MCD in adult populations, urging ongoing research for enhanced understanding and tailored management strategies. It emphasizes the pivotal role of physician awareness, alternative treatments, and continued investigation to improve outcomes for adults with MCD.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Cureus Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Cureus Ano de publicação: 2024 Tipo de documento: Article