[Heparin Resistance After Administration of Andexanet Alfa:Report of a Case].
Kyobu Geka
; 77(6): 454-456, 2024 Jun.
Article
em Ja
| MEDLINE
| ID: mdl-39009541
ABSTRACT
The management of patients on direct oral anticoagulants (DOACs) who require an emergency cardiac surgery has been disputed in Japan. Recently, the use of andexanet alfa as an antidote for apixaban and rivaroxaban, is approved in the setting of life-threating or uncontrollable major bleeding. However, the efficacy and safety of andexanet alfa have been investigated. We report a case of 72-year-old man taking rivaroxaban who required the emergency coronary artery bypass grafting. He received andexanet alfa prior to the operation. Heparin resistance was noted before starting cardiopulmonary bypass. Consideration should be given to the use of andexanet alfa before or during cardiopulmonary bypass.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas Recombinantes
/
Heparina
Limite:
Aged
/
Humans
/
Male
Idioma:
Ja
Revista:
Kyobu Geka
Ano de publicação:
2024
Tipo de documento:
Article