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Evidence-based review on symptomatic management of Huntington's disease.
Shin, Jung Hwan; Yang, Hui-Jun; Ahn, Jong Hyun; Jo, Sungyang; Chung, Seok Jong; Lee, Jee-Young; Kim, Hyun Sook; Kim, Manho.
Afiliação
  • Shin JH; Department of Neurology, Seoul National University Hospital & Seoul National University College of Medicine, Seoul, South Korea.
  • Yang HJ; Department of Neurology, Ulsan University Hospital, Ulsan, South Korea.
  • Ahn JH; Department of Neurology, Seoul Samsung medical center, Seoul, South Korea.
  • Jo S; Department of Neurology, Seoul Asan medical center, Seoul, South Korea.
  • Chung SJ; Department of Neurology, Yongin Severance Hospital, Yonsei University Health System, Yongin, South Korea.
  • Lee JY; Department of Neurology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center & Seoul National University College of Medicine, Seoul, South Korea.
  • Kim HS; Department of Neurology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, South Korea.
  • Kim M; Department of Neurology, Seoul National University Hospital & Seoul National University College of Medicine, Seoul, South Korea.
J Mov Disord ; 2024 Aug 09.
Article em En | MEDLINE | ID: mdl-39117301
ABSTRACT
Huntington's disease (HD) is a neurodegenerative disorder with a significant impact on patients' quality of life, characterized by motor, behavioral, and cognitive impairments. This evidence-based review, conducted by the Korean Huntington Disease Society (KHDS) task force, systematically examines current pharmacological and non-pharmacological interventions for symptomatic management of HD. Following PRISMA guidelines, databases were searched for studies up to August 2022, focusing on 23 symptoms across four domains motor, neuropsychological, cognition, and others. This review provides a comprehensive and systematic approach to the management of HD, highlighting the need for more high-quality clinical trials to develop robust evidence-based guidelines.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Mov Disord Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Mov Disord Ano de publicação: 2024 Tipo de documento: Article