A Case of Cholangitis as a Nivolumab-Induced Immune-Related Adverse Event in a Patient with Pulmonary Metastasis After Surgery for Oral Cancer.
J Maxillofac Oral Surg
; 23(4): 979-983, 2024 Aug.
Article
em En
| MEDLINE
| ID: mdl-39118937
ABSTRACT
We report a case of cholangitis, an immune-related adverse event (irAE), caused by the administration of nivolumab in a patient with lung metastasis of oral cancer. A 72-year-old man developed pulmonary metastasis after surgery for oral cancer. Hepatic enzyme abnormalities were observed after the second session of treatment, and irAE cholangitis was diagnosed based on the results of the blood test results and endoscopy findings. We suggested steroid treatment, but the patient refused it. Therefore, he was treated with ursodeoxycholic acid. The cholangitis gradually deteriorated, the patients' general condition worsened, and he died 169 days after the onset of cholangitis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
J Maxillofac Oral Surg
Ano de publicação:
2024
Tipo de documento:
Article