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A rare cutaneous infection with Mycobacterium chelonae in a pediatric patient treated with trametinib for KRAS-mutated diffuse glioma.
Ryan, Chenin; Moore, Angel; Davis, Matthew; Yazel, Caitlin; Momtahen, Shabnam; Ricci, Angela M; Talbot, Elizabeth A; Mann, Julianne; Pace, Nicole.
Afiliação
  • Ryan C; Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
  • Moore A; Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
  • Davis M; Department of Dermatology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA.
  • Yazel C; Department of Dermatology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA.
  • Momtahen S; Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
  • Ricci AM; Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.
  • Talbot EA; Section of Pediatric Hematology/Oncology, Department of Pediatrics, Children's Hospital at Dartmouth-Hitchcock, Lebanon, New Hampshire, USA.
  • Mann J; Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
  • Pace N; Infectious Disease and International Health, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.
Pediatr Dermatol ; 2024 Aug 15.
Article em En | MEDLINE | ID: mdl-39148304
ABSTRACT
Mitogen-activated extracellular signal-regulated kinase inhibitors (MEKi) represent a promising new therapy for pediatric patients with low-grade gliomas, which frequently have abnormal signaling within the mitogen-activated protein kinase (MAP kinase) pathway. However, understanding of long-term efficacy and toxicity is limited in pediatric glioma patients. This article describes a rare presentation of a widespread cutaneous infection with Mycobacterium chelonae in a pediatric patient with a low-grade glioma treated with trametinib.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pediatr Dermatol Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pediatr Dermatol Ano de publicação: 2024 Tipo de documento: Article