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A portal to highly valuable indole-functionalized vinyl sulfonyl fluorides and allylic sulfonyl fluorides.
Huang, Wenzhuo; Fayad, Eman; Abu Ali, Ola A; Qin, Hua-Li.
Afiliação
  • Huang W; State Key Laboratory of Silicate Materials for Architectures; and School of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan 430070, China. qinhuali@whut.edu.cn.
  • Fayad E; Department of Biotechnology, College of Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia. e.esmail@tu.edu.sa.
  • Abu Ali OA; Department of Chemistry, College of Science, Taif University, Taif 21944, Saudi Arabia. o.abuali@tu.edu.sa.
  • Qin HL; State Key Laboratory of Silicate Materials for Architectures; and School of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan 430070, China. qinhuali@whut.edu.cn.
Org Biomol Chem ; 22(35): 7117-7120, 2024 Sep 11.
Article em En | MEDLINE | ID: mdl-39150283
ABSTRACT
A practical and efficient method for the C-3 site selective alkenylation of indoles was developed for constructing novel indole-functionalized vinyl sulfonyl fluorides and indolyl allylic sulfonyl fluorides. The reaction is accomplished with exclusive regio- and stereoselectivity without using transition metal catalysts, providing novel products of great potential value in medicinal chemistry, chemical biology, and drug discovery.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Org Biomol Chem Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Org Biomol Chem Ano de publicação: 2024 Tipo de documento: Article