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Tailored-Biomaterials Based Potential Strategies for Cardiovascular Disease.
Bhullar, Sukhwinder K; Mondal, Haimanti; Thomas, John; Ruzgar, Duygu Gazioglu; Chandrasekaran, Natarajan; Mukherjee, Amitava; Jun, Martin B G; Willerth, Stephanie M.
Afiliação
  • Bhullar SK; Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, MB R2H 2A6, Canada.
  • Mondal H; Centre for Nanobiotechnology, Vellore Institute of Technology (VIT), 632014 Vellore, India.
  • Thomas J; Centre for Nanobiotechnology, Vellore Institute of Technology (VIT), 632014 Vellore, India.
  • Ruzgar DG; Polymer Materials Engineering, Bursa Technical University, 16310 Bursa, Turkey.
  • Chandrasekaran N; Centre for Nanobiotechnology, Vellore Institute of Technology (VIT), 632014 Vellore, India.
  • Mukherjee A; Centre for Nanobiotechnology, Vellore Institute of Technology (VIT), 632014 Vellore, India.
  • Jun MBG; School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA.
  • Willerth SM; Department of Mechanical Engineering, Division of Medical Sciences, University of Victoria, Victoria, BC V8W 2Y2, Canada.
Discov Med ; 36(187): 1544-1554, 2024 Aug.
Article em En | MEDLINE | ID: mdl-39190371
ABSTRACT
Cardiovascular disease is a significant health concern worldwide, and varied effective treatment and prevention methods have been developed. Among these, tailored biomaterials-based strategies such as stents, scaffolds, patches, and drug delivery systems have emerged as a promising avenue. These devices are designed to match the mechanical and biological mechanisms of the cardiovascular system, ensuring optimal performance and compatibility. By effectively treating or preventing cardiovascular diseases, these devices have the potential to improve patient health outcomes significantly. They can restore blood flow by addressing blocked arteries and regenerate damaged cardiac tissue by delivering bioactive agents or cells directly to the affected area in a targeted, sustained, and controllable manner. Therefore, the objective of this article is to summarize the available evidence on these tailored biomaterial-based tunable cardiovascular devices. This knowledge can help to transform cardiovascular medicine for the treatment or prevention of cardiovascular disease and restore cardiac function to improve patients' quality of life.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Materiais Biocompatíveis / Doenças Cardiovasculares Limite: Animals / Humans Idioma: En Revista: Discov Med Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Materiais Biocompatíveis / Doenças Cardiovasculares Limite: Animals / Humans Idioma: En Revista: Discov Med Ano de publicação: 2024 Tipo de documento: Article