Alternating binding and p97-mediated dissociation of SDS22 and I3 recycles active PP1 between holophosphatases.

Kueck, Anja F; van den Boom, Johannes; Koska, Sandra; Ron, David; Meyer, Hemmo

Kueck, Anja F; van den Boom, Johannes; Koska, Sandra; Ron, David; Meyer, Hemmo.

Afiliação

Kueck AF; Molecular Biology I, Center of Medical Biotechnology, Faculty of Biology, University of Duisburg-Essen, 45141 Essen, Germany.
van den Boom J; Molecular Biology I, Center of Medical Biotechnology, Faculty of Biology, University of Duisburg-Essen, 45141 Essen, Germany.
Koska S; Molecular Biology I, Center of Medical Biotechnology, Faculty of Biology, University of Duisburg-Essen, 45141 Essen, Germany.
Ron D; Cellular Pathophysiology and Clinical Biochemistry, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
Meyer H; Molecular Biology I, Center of Medical Biotechnology, Faculty of Biology, University of Duisburg-Essen, 45141 Essen, Germany.

Proc Natl Acad Sci U S A ; 121(36): e2408787121, 2024 Sep 03.

Article em En | MEDLINE | ID: mdl-39207734

Assuntos

Proteína Fosfatase 1; Proteína Fosfatase 1/metabolismo; Humanos; Ligação Proteica; Adenosina Trifosfatases/metabolismo; Proteínas de Ciclo Celular/metabolismo; Holoenzimas/metabolismo; Transferência Ressonante de Energia de Fluorescência; Fosforilação; Proteína Fosfatase 2C

Palavras-chave

AAA+ ATPase; Förster resonance energy transfer; VCP; protein phosphatase-1; protein unfolding

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Fosfatase 1 Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2024 Tipo de documento: Article

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