[Reye's syndrome a clinical and electrophysiological study of four patients (author's transl)]. / Le syndrome de reye étude électroclinique de quatre observations.
Rev Electroencephalogr Neurophysiol Clin
; 7(4): 479-85, 1977.
Article
em Fr
| MEDLINE
| ID: mdl-611596
ABSTRACT
The authors studied four children with Reye's syndrome aged 16 months, 6 years, 8 years and 11 years respectively with severe liver failure and progressive coma. The laboratory investigations in all of them showed a marked elevation of serum transaminases, hyperammoniaemia and a prolongation of the prothrombin time. The electroencephalograms showed a grossly abnormal picture with generalised continuous delta activity. Three children survived with return to normal of the liver function tests whilst the fourth child died. In the last two patients an electroencephalogram carried out every six hours has enabled certain prognostic features to be determined. Improvement in the E.E.G. correlates closely with clinical improvement and vice versa. The authors also advocate serial E.E.G. recordings in Reye's syndrome. The role of hyperammonaemia in the genesis of encephalopathy and the electroencephalographic changed is discussed. The role played by raised intracranial pressure is stressed and the importance of controlling it in order to prevent further damage and improve the prognosis of this serious illness.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome de Reye
Tipo de estudo:
Prognostic_studies
Limite:
Child
/
Female
/
Humans
/
Infant
/
Male
Idioma:
Fr
Revista:
Rev Electroencephalogr Neurophysiol Clin
Ano de publicação:
1977
Tipo de documento:
Article