Co-localization of neurophysin- and enkephalin-like immunoreactivity in cat pituitary.
Peptides
; 2 Suppl 1: 51-5, 1981.
Article
em En
| MEDLINE
| ID: mdl-6167969
ABSTRACT
Enkephalin and neurophysin immunoreactivity have been co-localized in terminals of frozen-dried cat posterior pituitary, using two methods of immunocytochemistry--the protein A-gold procedure and the PAP method. Absorption controls show reduced staining in all cases. Intermediate lobe cells are negative using the enkephalin and neurophysin antisera, but with alpha-MSH antiserum, posterior lobe terminals are negative and intermediate lobe cells are positive. The data are compatible with the hypothesis that inhibition of release of oxytocin and vasopressin by the pituitary opioid system is accomplished by an autoregulatory mechanism in which the release of enkephalin with oxytocin or vasopressin serves to inhibit release of the neurohormones.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hipófise
/
Encefalinas
/
Neurofisinas
/
Endorfinas
Limite:
Animals
Idioma:
En
Revista:
Peptides
Ano de publicação:
1981
Tipo de documento:
Article