Electrical measurement of electroneutral fluxes of divalent cations through charged planar phospholipid membranes.
Biochim Biophys Acta
; 688(3): 793-7, 1982 Jun 28.
Article
em En
| MEDLINE
| ID: mdl-6288093
ABSTRACT
The voltage-sensitive channel-former monazomycin is used as a conductance probe to monitor changes in the trans electrostatic surface potentials of negatively-charged planar phospholipid bilayers. Cis-to-trans electroneutral fluxes of divalent cations mediated by ionophores A23187 and X537A are sensed via the effect of transported divalent cations on the trans surface potentials. Quantitative determinations of neutral Ca2+ and Mg2+ fluxes are made and related to ionophore function.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cátions Bivalentes
/
Macrolídeos
/
Bicamadas Lipídicas
/
Antibacterianos
Idioma:
En
Revista:
Biochim Biophys Acta
Ano de publicação:
1982
Tipo de documento:
Article