Concerning the decarboxylation of 3-carboxysalsolinol.
Subst Alcohol Actions Misuse
; 3(5): 281-5, 1982.
Article
em En
| MEDLINE
| ID: mdl-6820193
ABSTRACT
3-Carboxysalsolinol (14C-COOH) was prepared from DOPA (1-14C). Both in vitro and in vivo studies were conducted to examine the possibility that this amino-acid tetrahydroisoquinoline is converted to salsolinol in a parallel manner to the formation of dopamine from its amino-acid precursor. The results showed that this is not so for DOPA is decarboxylated far more readily than is 3-carboxysalsolinol. Small quantities of carbon dioxide (14C) are liberated from 3-carboxysalsolinol (14C-COOH), but this may reflect non-enzymatic decarboxylation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Alcaloides de Salsolina
/
Isoquinolinas
Limite:
Animals
Idioma:
En
Revista:
Subst Alcohol Actions Misuse
Ano de publicação:
1982
Tipo de documento:
Article