Gene for hereditary retinoblastoma assigned to human chromosome 13 by linkage to esterase D.
Science
; 219(4587): 971-3, 1983 Feb 25.
Article
em En
| MEDLINE
| ID: mdl-6823558
ABSTRACT
Evaluation of three families with hereditary retinoblastoma demonstrates close linkage of the gene for this tumor with the genetic locus for esterase D. These results assign the gene for the hereditary form of retinoblastoma to band q14 on chromosome 13, the same region which is affected in the chromosome deletion form of this eye tumor, and therefore suggest a common underlying mechanism in the pathogenesis of these two forms of retinoblastoma.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Retinoblastoma
/
Cromossomos Humanos 13-15
Limite:
Humans
Idioma:
En
Revista:
Science
Ano de publicação:
1983
Tipo de documento:
Article