Effects of shipping on the immune function in mice.
Am J Vet Res
; 43(9): 1654-7, 1982 Sep.
Article
em En
| MEDLINE
| ID: mdl-7149414
ABSTRACT
The effect of shipping stress on immunologic functions was examined in mice. The mice were shipped either by truck or by plane, 2 of the most common modes for transport of animals. While mice were in transit, temperature fluctuations and light intensity were monitored. The foot pad test, hemagglutination assay, and plaque-forming cell assay were used to measure immunologic function. Corticosterone concentrations were quantitated with a competitive protein-binding technique. Regardless of the method of shipment, corticosterone values in the mice were markedly increased at arrival and remained at the high value for a 48-hour period. Immune-function assays were significantly lessened in the mice at arrival, but returned to base line within 48 hours, indicating that a minimum 48-hour stabilization period is required for all new arrivals.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças dos Roedores
/
Estresse Fisiológico
/
Meios de Transporte
/
Camundongos
Limite:
Animals
Idioma:
En
Revista:
Am J Vet Res
Ano de publicação:
1982
Tipo de documento:
Article