Free sphingosines in oral epithelium.
Comp Biochem Physiol B Biochem Mol Biol
; 110(3): 511-3, 1995 Mar.
Article
em En
| MEDLINE
| ID: mdl-7584827
ABSTRACT
Free sphinogosines, intermediates in the biosynthesis of ceramides and inhibitors of protein kinase C, have been found to be present in significant concentrations in epidermis and oral epithelia of the pig (Sus scrofa). Concentrations of sphingosines were higher in the outer portion of epidermis (4.4 mg/g), palatal epithelium (3.9 mg/g) and buccal epithelium (0.7 mg/g) compared to the inner portion of the epithelia (1.0, 0.9 and 0.4 mg/g, respectively). Free sphingosines may provide antimicrobial activity at the epithelial surfaces, and the sphingosine gradient may modulate epithelial differentiation.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esfingosina
/
Boca
Limite:
Animals
Idioma:
En
Revista:
Comp Biochem Physiol B Biochem Mol Biol
Ano de publicação:
1995
Tipo de documento:
Article