Occurrence of the regulatory nucleotides ppGpp and pppGpp following induction of the stringent response in staphylococci.
J Bacteriol
; 177(17): 5161-5, 1995 Sep.
Article
em En
| MEDLINE
| ID: mdl-7665499
ABSTRACT
The stringent response in Escherichia coli and many other organisms is regulated by the nucleotides ppGpp and pppGpp. We show here for the first time that at least six staphylococcal species also synthesize ppGpp and pppGpp upon induction of the stringent response by mupirocin. Spots corresponding to ppGpp and pppGpp on thin-layer chromatograms suggest that pppGpp is the principal regulatory nucleotide synthesized by staphylococci in response to mupirocin, rather than ppGpp as in E. coli.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
3_ND
Base de dados:
MEDLINE
Assunto principal:
Staphylococcus aureus
/
Adaptação Biológica
/
Aminoácidos
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Guanosina Pentafosfato
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Guanosina Tetrafosfato
Idioma:
En
Revista:
J Bacteriol
Ano de publicação:
1995
Tipo de documento:
Article