Transurethral microwave treatment for benign prostatic hypertrophy: a randomised controlled clinical trial.
BMJ
; 306(6888): 1293-6, 1993 May 15.
Article
em En
| MEDLINE
| ID: mdl-7686065
ABSTRACT
OBJECTIVES:
To determine whether transurethral microwave treatment for patients with benign prostatic hypertrophy provides significant symptomatic relief, a reduction in residual urine volumes, and improvements in flow rates compared with sham treatment.DESIGN:
Prospective double blind randomised study with follow up at three months.SETTING:
Department of Urology in a London teaching hospital. PATIENTS 40 men completed the study 22 received microwave treatment and 18 received sham treatment. Entry criteria were symptoms of prostatism of at least six months' duration, a total symptom score > 14, and a peak urine flow rate < 15 ml/s or a residual urine volume > 50 ml. Exclusion criteria were prostatic cancer, a residual urine volume > 200 ml, a very large prostate, an obstructing middle lobe, acute urinary retention, impaired renal function, coexisting urinary tract disease, and previous prostatic surgery.INTERVENTIONS:
A single 90 minute transurethral microwave treatment or sham treatment. OUTCOMEMEASURES:
Patients' symptoms (including daytime frequency and nocturia) recorded in a self assessment symptom score questionnaire, peak urinary flow rates, and residual urine volumes.RESULTS:
The mean total symptom scores of the patients who received microwave treatment fell from 30 to 11 compared with a fall from 31 to 26 for patients who received sham treatment (p < 0.001). Among patients who received microwave treatment daytime frequency fell from 9.4 to 5.5 voids a day and night time frequency from 3.5 to 1.6 voids a night; residual urine volumes fell from 104 ml to 52 ml; and peak urine flow rates increased by 2.3 ml/s. In the control group there was no improvement in any of these features. Treatment preserved sexual function and antegrade ejaculation.CONCLUSIONS:
For selected patients with prostatism microwave treatment is effective and has few side effects.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hiperplasia Prostática
/
Micro-Ondas
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Observational_studies
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Risk_factors_studies
Limite:
Humans
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Male
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Middle aged
Idioma:
En
Revista:
BMJ
Ano de publicação:
1993
Tipo de documento:
Article