Pathways of cysteine metabolism in MND/ALS.

Pean, A; Steventon, G B; Waring, R H; Foster, H; Sturman, S; Williams, A C

Pean, A; Steventon, G B; Waring, R H; Foster, H; Sturman, S; Williams, A C.

Afiliação

Pean A; School of Biochemistry, University of Birmingham, Edgbaston, UK.

J Neurol Sci ; 124 Suppl: 59-61, 1994 Jul.

Article em En | MEDLINE | ID: mdl-7807143

ABSTRACT

ABSTRACT

Analysis of plasma from MND/ALS patients has shown no significant differences in metabolism of cysteine derivatives, although a sub-set of the population has raised glutamate values. Cysteine dioxygenase was found to have reduced activity in vitro, consistent with previous findings of a high plasma cysteine/sulphate ratio.

Assuntos

Esclerose Lateral Amiotrófica/metabolismo; Cisteína/metabolismo; Dioxigenases; Doença dos Neurônios Motores/metabolismo; Adulto; Aminoácidos/sangue; Cromatografia Líquida de Alta Pressão; Cisteamina/sangue; Cisteína Dioxigenase; Humanos; Oxigenases/metabolismo; Ranitidina/sangue

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença dos Neurônios Motores / Cisteína / Dioxigenases / Esclerose Lateral Amiotrófica Limite: Adult / Humans Idioma: En Revista: J Neurol Sci Ano de publicação: 1994 Tipo de documento: Article

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