Identification, characterization, and physical mapping of 14 polymorphic simple sequence repeat markers on human chromosome 21.
Genomics
; 21(3): 633-7, 1994 Jun.
Article
em En
| MEDLINE
| ID: mdl-7959742
ABSTRACT
Fourteen new dinucleotide repeat polymorphisms specific for human chromosome 21 have been identified, mapped, and characterized. The average heterozygosity of all markers was 0.66. The average PIC value was 0.61. The markers were mapped by STS content mapping of YACs previously assigned to chromosome 21. The correlation of polymorphic genetic markers with substantially complete physical maps should facilitate the identification of loci of interest on chromosome 21.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cromossomos Humanos Par 21
/
Sequências Repetitivas de Ácido Nucleico
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Genomics
Ano de publicação:
1994
Tipo de documento:
Article