[Constitutional translocation t(1;6) and Burkitt's lymphoma]. / Translocation constitutionnelle t(1;6) et lymphome de Burkitt.
Arch Pediatr
; 1(6): 582-6, 1994 Jun.
Article
em Fr
| MEDLINE
| ID: mdl-7994351
ABSTRACT
BACKGROUND:
The relationship between constitutional chromosome aberrations and a predisposition to malignancy has already been established. CASE REPORT A 4 year-old boy was admitted suffering from abdominal mass. Biopsies of the tumor and bone marrow showed a stage IV Burkitt's lymphoma. Karyotype showed a constitutional t(1;6)(p36;q22) in initial bone marrow samples and peripheral lymphocytes. No classic Burkitt's type translocation was demonstrated in the malignant bone marrow cells.CONCLUSION:
Our case is similar to four other reported cases. The break-points 1p36 and 6q22 seem to be involved in several malignant tumors, especially lymphomas.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Translocação Genética
/
Cromossomos Humanos Par 1
/
Cromossomos Humanos Par 6
/
Linfoma de Burkitt
Limite:
Child, preschool
/
Humans
/
Male
Idioma:
Fr
Revista:
Arch Pediatr
Ano de publicação:
1994
Tipo de documento:
Article